Clinical Protocol Dosage
Take 2 capsules daily with water, preferably with a meal or as directed by your healthcare professional.
Supplement Facts
Serving Size: 2 Capsules
Servings per Container: 30
Amount per Serving
% DV
Organic Ashwagandha Extract (Withania somnifera) (Root)
600 mg **
Sensoril® Ashwagandha Extract (Withania somnifera) (Root and Leaf)
250 mg **
Gut-Brain Probiotics Blend (10 Billion CFU)
Lactobacillus helveticus, Bifidobacterium longum, Lactobacillus rhamnosus, Bifidobacterium animalis lactis
100 mg **
L-Theanine
100 mg **
Organic Rhodiola Extract (Rhodiola rosea) (Root)
100 mg **
Organic Siberian Ginseng Extract (Eleutherococcus senticosus) (Root)
100 mg **
Organic Saffron Extract (Crocus sativus L.) (Stigma)
30 mg **
Organic Black Pepper Extract (Piper nigrum) (Fruit)
5 mg **
Other ingredients: Pullulan capsule, organic rice hulls.
Certified Organic
100% Vegan
Non-GMO
Gluten Free
The Neuro-Endocrine Protocol
Stop treating stress superficially.
Stop treating stress superficially.
Rewire your Gut-Brain Axis.
PROTOCOL 01
The Psychobiotic Matrix
Anxiety doesn't just live in your head; it starts in your gut. Over 90% of your body's serotonin is produced in the digestive tract. We engineered a 10 Billion CFU multi-strain probiotic blend designed specifically to repair the physical communication bridge between your microbiome and your brain's mood centers.
PROTOCOL 02
Clinical Cortisol Reset
Powered by Sensoril® Ashwagandha. This patented extract is clinically proven to lower Cortisol (the aging & belly-fat stress hormone), rescuing your adrenal glands from chronic burnout.
PROTOCOL 03
Serotonin Synthesis
Formulated with Affron® Saffron. Backed by 9 human clinical trials to actively elevate mood, reduce emotional exhaustion, and establish a resilient psychological baseline.
PROTOCOL 04
Calm, Non-Sedated Focus
The synergistic blend of L-Theanine, Rhodiola, and Siberian Ginseng clears "brain fog" and generates Alpha brain waves. Experience razor-sharp cognitive clarity without the jittery anxiety of caffeine.
Patented Potency
We don't use generic herb powders.
Your nervous system requires precise, standardized extracts. We partnered with the world's leading botanical research labs to source ingredients backed by double-blind, placebo-controlled human clinical trials.
Sensoril®
Advanced Ashwagandha Root & Leaf Extract
The Ultimate Cortisol Modulator
Standard Ashwagandha only uses the roots. Sensoril® utilizes a proprietary blend of both leaves and roots, resulting in a concentration of Withanolide glycosides that is up to 8x more potent than generic extracts. It directly targets the adrenal glands to lower physiological stress markers.
8X
More Potent Than Standard Root
10%
Standardized Withanolides Minimum
Affron®
Premium Standardized Saffron Extract
Clinically Proven Mood Elevation
Extracted using an eco-friendly proprietary process (AFF® ON Cool-Tech) to preserve the potent bioactive compounds (Lepticrosalides). Affron® is the most clinically researched saffron extract in the world, proven to naturally support serotonin and dopamine synthesis for a resilient, positive mood.
9
Human Clinical Trials Completed
100%
DNA-Certified Spanish Origin
What To Expect
The Path to Biological Resilience
True emotional baseline repair doesn't happen overnight. While some botanical ingredients offer immediate calm, the psychobiotics and adaptogens take weeks to fundamentally rewire your stress response.
Days 1 - 3
Acute Tension Release
Within the first few days, L-Theanine and Saffron initiate a noticeable shift in brain wave activity (promoting Alpha waves). You will likely feel a subtle but distinct "taking the edge off" effect—experiencing calm focus during the day without drowsiness.
Weeks 2 - 4
The Gut-Brain Bridge Opens
The 10 Billion CFU Psychobiotic blend begins colonizing your gut microbiome. As intestinal inflammation decreases, the natural production of serotonin optimizes. Digestion issues often linked to anxiety (like "nervous stomach") begin to settle.
Weeks 8+
Endocrine Recalibration & Cortisol Mastery
Sensoril® Ashwagandha reaches clinical efficacy levels in your system. Chronic cortisol levels drop significantly. You may notice better sleep architecture, reduced adrenal fatigue, and an easier time managing stress-induced "belly fat" and emotional eating.
SENSORIL® is a patent organic ashwagandha leaf and root extract with a high level of bioactive withanolide glycosides. SENSORIL® has been studied in 14 scientific studies and proven to support focus and reaction time, maintain a positive mood. SENSORIL® also supports long-lasting energy.
AFFRON® is a natural saffron stigma extract sourced from Spain. AFFRON® has been tested in 3 scientific studies. AFFRON® is shown to maintain a positive mood, improve relaxation and focus, and improve rest quality. AFFRON® is also supportive for menopausal women who experience hot flashes and sweating.
The connection between the brain and gut, gut-brain axis, was recently discovered by scientists. Gut-brain axis is the two-way connection and communication between gut and brain. What is happening in the gut can directly influence our brain function and behavior and vise versa.
Science has revealed a disrupted balance of gut microorganisms has significant impact on neurological health. Supplementation of probiotics can restore balance of gut microorganisms and promote overall health.
Probiotics are beneficial microorganisms that can provide health benefits when ingested. UpNourish Joyful includes 11 clinically tested strains to balance gut microenvironment and support positive mood.
Adaptogens are herbs that help the body adapt to emotional ups and downs. Adaptogens have been used for centuries . Popular adaptogens are Ashwagandha, Asian Ginseng, American Ginseng, Siberian Ginseng, Maca, Rhodiola, Holy Basil, Turmeric and Astragalus.
UpNourish Joyful not only contains adaptogens but also contains Theanine, a natural extract from green tea, to soothe emotional tension.
In a world of constant demands, 77% of Americans feel the physical effects of their hectic pace. UpNourish Joyful is designed to nourish your mind and body, promoting a balanced state of well-being with its powerful blend of ingredients.